The partnership drew scrutiny because of Flock’s reported ties to federal agencies. But the Flock spokesperson dismissed these ties as rumors, saying: “We do not have any contracts with any of them, which means they cannot directly access data on the platform.”
By the time Sanger sequencing was commercialized, the groundwork for an entirely new sequencing chemistry was already well underway. In 1985, Swedish biochemists Pål Nyren and Arne Lundin published a paper illustrating a procedure that measured the concentration of a molecule, called pyrophosphate (PPi), using an enzymatic cascade that emits light. In early 1986, Nyren realized that the method he’d helped develop could be applied to DNA sequencing, because PPi is naturally produced as a byproduct of DNA synthesis.5，这一点在PDF资料中也有详细论述
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